Issue No. 20Week ending Sunday, May 17, 2026621 episodes · 2738 articles
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Understanding & Controlling Aggression | Huberman Lab Essentials

With Andrew Huberman · Sunday, May 17, 2026

Andrew Huberman discusses the biological underpinnings of aggression, differentiating between types like reactive and proactive aggression and dispelling common myths. He explains the critical role of the ventromedial hypothalamus (VMH) and estrogen (not testosterone directly) in triggering aggressive behaviors, heavily influenced by environmental factors like day length and stress hormones. The episode concludes with actionable strategies to modulate aggressive tendencies, including lifestyle adjustments and specific supplements.

Key takeaways

  • Acetyl L-Carnitine (ALCAR) significantly reduces aggression and impulsivity. A randomized, double-blind, placebo-controlled, double-crossover study in children with ADHD showed clear benefits. Read more →

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