How the OpenAI team uses ChatGPT Sites daily
OpenAI Product Lead Kath Korevec joins host Claire Vo at OpenAI DevDay to showcase the practical and creative applications of ChatGPT Sites and Codex. They exp…
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AI podcast summaries.
Building with AI, investing in AI, and the people shaping it. Lenny's Podcast, How I AI, No Priors, Latent Space. Covering How I AI, Latent Space, Lenny's Podcast, No Priors, Practical AI.
124 episodesin ai
588 articlescovered
588 articlescovered
The Future of Claude Code: Mods, Mutable Software, & Multiplayer Agents — Thariq Shihipar, Anthropic
Anthropic's Thariq Shihipar joins swyx and Vibhu to discuss the evolution of Claude Code, the introduction of Claude Mods, and the architectural future of muta…
I’m using Jev more than Opus 5.5 or GPT-6. Here’s why.
Claire Vo breaks down TypeSafe AI's decision model Jev, explaining how its low cost and typed output primitives (choice, score, and boolean likelihood) enable…
Where AI products go next: voice, agents, and self-driving software | Tara Sesha and Nan Yu (OpenAI)
OpenAI product leaders Tara Seshan and Nan Yu join Claire Vo at the Lenny and Friends Summit to discuss the realities of building AI products in a fast-moving…
Roles aren't converging—they're expanding | Tamar Yehoshua (Atlassian CPO)
Atlassian Chief Product Officer Tamar Yehoshua explores how generative AI is expanding the role of product managers rather than replacing them. Using internal…
OpenAI’s Head of ChatGPT: We’re entering a new era of AI (again) | Tibo Sottiaux
Tibo Sottiaux, Head of ChatGPT and Codex at OpenAI, joins Lenny Rachitsky at DevDay to discuss the launch of Dots, OpenAI's new autonomous personal agent platf…
Frontier Chips for Frontier AI Labs, with Walter Goodwin, Founder/CEO of Fractile
Walter Goodwin, founder and CEO of AI chip startup Fractile, joins Sarah Guo to discuss the technical and commercial landscape of frontier AI inference silicon…
Context is now the product: Product leadership when software can build itself | Karri Saarinen
Linear co-founder and CEO Karri Saarinen delivers a keynote at the Lenny and Friends Summit examining how AI changes product development. He argues that optimi…
The rise of HI-ICs | Elena Verna (Lovable)
Elena Verna discusses the emergence of the High-Impact Individual Contributor (HI-IC) role in the AI era and how building tools like Lovable allow experienced…
OpenAI DevDay 2026: Dots, Spaces, and ULTRAFAST
Claire Vo recaps the major product announcements from OpenAI DevDay 2026 in San Francisco. She shares hands-on testing results for OpenAI's new autonomous agen…
Open models and the future of Physical AI with NVIDIA
Ming-Yu Liu, Vice President of Cosmos Lab at NVIDIA, joins Daniel Whitenack and Chris Benson to discuss the critical role of open foundation models and world m…
Why Claude can’t be your PM (yet) | Anthropic CPO Panel
Anthropic product leaders Ami Vora and Mike Krieger join Dan Shipper at the Lenny and Friends Summit to discuss the evolving role of product management in the…
What it takes to be a top PM today | Robby Stein (Google Search)
Google Search product leader Robby Stein delivers a keynote on the evolving craft of product management in the AI era. Drawing on his experience launching Inst…
Which GPU Clouds Are Actually Good? | ClusterMAX 3.0
SemiAnalysis researchers Jordan and Dylan join swyx to break down the findings of ClusterMAX 3.0, evaluating the managed GPU cloud landscape. They analyze seve…
Jev: 8 real use cases this fast, cheap model
Claire Vo and John Lindquist discuss Jev, an ultra-fast, low-cost decision and classification model from Typesafe AI. They explore architectural patterns and r…
Recursive Language Models — Alex Zhang, MIT PhD
MIT researcher Alex Zhang discusses Recursive Language Models (RLMs), the mechanics of harness design, and why modern coding agents share common underlying arc…
OpenAI’s New Agent Stack: Computer Use, Decisions API, UltraFast, Dots—Ari Weinstein & Nikunj Handa
Recorded immediately following OpenAI DevDay, Ari Weinstein and Nikunj Handa join the hosts to detail OpenAI's newest agent and API announcements. Weinstein ex…
🔬Bio-security is an AI Arms Race - Eric Nguyen (CEO, Radical Numerics)
Eric Nguyen, CEO and co-founder of Radical Numerics and creator of the Evo models, joins hosts Brandon and R.J. Honiki to discuss the evolution of genome langu…
Claude is BACK with Opus 5.5
Claire Vo reviews Anthropic's Claude Opus 5.5 after stepping away from Claude models due to verbose and preachy responses. She evaluates its pricing, tone chan…
🔬 Google's AI Scientist Started as an Attempt to Automate Kaggle — John Platt, Google Fellow
Google Fellow John Platt discusses Google's Empirical Research Assistance (ERA) framework, an agentic AI system combining LLMs with Monte Carlo tree search to…
How to build products on a moving frontier | Dan Shipper (Every)
Every co-founder and CEO Dan Shipper explains how product teams can innovate on rapidly advancing AI frontiers by separating divergent lab experimentation from…
Raise the ceiling: how to scale intent, quality, and artistry with Al | Katie Dill (Stripe)
In this keynote from the Lenny and Friends Summit, Stripe Head of Design Katie Dill compares the current AI software boom to the post-WWII construction surge t…
Re-Founding Incumbents for the AI Era with Sequence Holdings Co-Founder and CEO Michael Lee
Sequence Holdings co-founder and CEO Michael Lee joins Sarah Guo to explain his strategy of transforming legacy incumbents through frontier engineering and a p…
The last roadmap | Claire Vo
In her keynote at the Lenny and Friends Summit, product executive Claire Vo argues that the traditional feature roadmap is obsolete in the era of AI-driven cod…
The $10 Trillion Token Economy — Alex Atallah, OpenRouter & Anjney Midha, AMP
OpenRouter co-founder Alex Atallah and AMP founder and CEO Anjney Midha, a former a16z general partner, join swyx to discuss the explosive rise of multi-model…
Runway’s Bet Beyond Video: World Models, Robotics, and the Neural OS — Anastasis Germanidis
Runway co-founder Anastasis Germanidis discusses the evolution of generative video into general-purpose world models, robotics simulators, and real-time neural…
From AGENTS.md to Enterprise Deployment
Nick Kuhn from VMware Tanzu Platform joins Daniel Whitenack and Chris Benson to discuss the realities of deploying AI agents in enterprise environments. They e…
The grief, loneliness, and burnout sweeping through the tech industry right now
Molly Graham revisits her famous 'Give Away Your Legos' career advice, explaining why delegating to AI is fundamentally different from delegating to humans. Sh…
Opus 5.5 is great (but GPT-6 Sol is better)
Claire Vo runs a live, blind benchmarking session comparing OpenAI's GPT-6 Sol and GPT-6 Astra against Anthropic's Claude Opus 5.5 across real-world workflows…
The limiting factor—how to design an AI software factory for speed | Geoff Charles (Ramp CPO)
Ramp Chief Product Officer Geoff Charles outlines how product organizations must transition from focusing solely on individual output to engineering an AI-powe…
Marty Cagan: Strong Opinions, loosely held
In a keynote address at the Lenny and Friends Summit, Marty Cagan outlines the top ten regrets about the product management advice he has given over the past t…
How we built Grok Bot in a month | Roman Ugarte (SpaceXAI)
Roman Ugarte, product lead at SpaceXAI and former Head of Growth at Cursor, details how a small, isolated team built and launched Grok Bot in just seven weeks.…
Computer-Use Agents and the Future of the Agentic Internet
Chris Benson and Demetrios Brinkmann discuss the rapid evolution of AI agents, focusing on the Agentic AI Foundation's governance of Model Context Protocol (MC…
Stripe built a company brain: Meet Kai
Sharadh Krishnamurthy, engineering manager at Stripe, joins Claire Vo to break down Kai, Stripe's internal AI agent used by over 10,000 employees weekly. He ex…
Inside the Team That Killed Mandatory Code Review — Quinn Slack, AMP
Quinn Slack, co-founder of AMP and former CEO of Sourcegraph, joins swyx to discuss how AI agents have completely altered software engineering workflows. They…
Coinbase’s Everything Exchange: Agentic Finance, Stablecoins & Tokenization with CEO Brian Armstrong
Coinbase co-founder and CEO Brian Armstrong joins Elad Gil to discuss the convergence of artificial intelligence and crypto infrastructure. They explore the cr…
GPT-6 Astra blew away every one of my benchmarks
Claire Vo shares her early access hands-on review of OpenAI's GPT-6 Astra model, demonstrating how its computer use and coding capabilities exceed prior models…
Trillion Token Context. No, Really — Anima Anandkumar & Benedikt Jenik, Accelerated Understanding
Accelerated Understanding co-founders Anima Anandkumar and Benedikt Jenik discuss building a foundational, multi-physics model that learns physical dynamics ac…
7 Grok Bot agents I use every day
Claire Vo explains why she migrated roughly 30 active agents from OpenClaw to Grok Bot, breaking down the platform's core primitives: bots, multi-account plugi…
I built a Claude Cowork system that does a week of PM work in a day
Daniel Blum, a product manager at Melio, details his comprehensive Claude and Cowork personal productivity system that compresses a week of PM overhead into a…
The Inference Frontier: from 100 to 10,000 tokens per second — Sean Lie, Cerebras CTO
Cerebras co-founder and CTO Sean Lie joins swyx following Hot Chips to discuss the launch of the CS-4 wafer-scale system, preview the roadmap to 10,000 tokens…
Why companies are becoming a series of loops | Anish Acharya (a16z)
Anish Acharya, General Partner at Andreessen Horowitz (a16z), explains why fears of a permanent underclass displaced by AI are overblown and how company buildi…
Redefining Chip Architecture with Arm CEO Rene Haas
Arm CEO Rene Haas discusses Arm's strategic transition from intellectual property licensing into custom physical silicon production, including the Arm AGI CPU…
AI’s third era: the rise of persistent AI coworkers | Tara Seshan (OpenAI’s product lead)
Tara Seshan, product lead for ChatGPT Work and Codex at OpenAI, joins Lenny Rachitsky to discuss how AI is shifting knowledge work from task execution ('rowing…
🔬 Why Transformers Hit a Wall the Moment Physics Shows Up — Anima Anandkumar, Caltech
Caltech professor and former NVIDIA AI research leader Anima Anandkumar discusses why traditional deep learning and transformers fail when applied to complex p…
Rethinking Legacy Data Infrastructure with Eon Co-Founders Ofir Ehrlich and Gonen Stein
Eon co-founders Ofir Ehrlich and Gonen Stein join Elad Gil to discuss how the rise of AI is transforming backup and disaster recovery into an active data found…
⏭️ Forward Deployed: Voice AI on what works in 2026
In this Forward Deployed Engineering panel hosted by Basil Chatha, engineering leaders from Daily, Decagon, Vapi, Retell AI, and Smallest AI discuss the realit…
How I manage 15 AI agents 24/7 as a solo founder | Ryan Carson
Solo founder Ryan Carson joins host Claire Vo to discuss how he manages 10 to 15 autonomous Devin agents in the cloud to ship dozens of daily PRs for Untangle.…
How I use ChatGPT to run my fashion business
Claire Vo interviews Yana Welander about her AI-native fashion startup, Yana Banana. Welander details how she leverages AI throughout the entire business proce…
Simulating Humanity: from Generative Agents to 8 Billion Digital Twins — Joon Sung Park, Simile AI
Joon Sung Park, co-founder and CEO of Simile AI and lead author of the landmark Generative Agents ('Smallville') paper, details his journey from artist to Stan…
84 minutes of enterprise sales alpha | Jen Abel
Jen Abel, co-founder of JJellyfish and GM of enterprise sales at State Affairs, walks step by step through the end-to-end enterprise sales cycle. She explains…
From Restoring Sight to Reimagining the Brain, with Max Hodak
Max Hodak, co-founder and CEO of Science Corporation, joins Sarah Guo to discuss PRIMA, Science's retinal implant that restores functional form vision to blind…
How Nuclear Will Unlock Energy Abundance with Valar Atomics Founder Isaiah Taylor
Isaiah Taylor, CEO of Valor Atomics, discusses their approach to rapidly scale nuclear fission through hardware iteration and manufacturing, contrasting it wit…
Exo: Harnesses should see their own code and logs — Alex Krentsel, UC Berekeley / Google Research
This episode features Alex Krentsel discussing Exo, a novel AI agent designed for fully recursive self-improvement. He explains how Exo's unique three-layer ha…
OpenAI’s Head of Design: This is the best time in history to be a designer | Ian Silber
Lenny Rachitsky discusses his survey finding designers as the unhappiest in tech, a sentiment Ian Silber attributes to uncertainty surrounding AI's impact on t…
🔬Biology Is Turning Into Software — Matt McPartlon and Neil Patil, Chai Discovery
This episode features Matt McPartlon and Neil Patil from Chai Discovery, a protein design startup, discussing their AI models (Chai 1, 2, and 3) for protein an…
The playbook for building high talent density teams | Adam Ward, Head of Talent at Cursor
Lenny Rachitsky and Adam Ward discuss how to build elite, high talent density teams by moving beyond the traditional 'funnel of doom' recruiting. They explore…
Chasing Trillion-Dollar Companies, Founder Ambition, Token Budgets, & Regulatory Capture
Sarah Guo and Elad Gil discuss the rapid rise of trillion-dollar AI companies, questioning the sustainability of such velocity and whether founders are becomin…
How this OpenAI engineer uses Codex + ChatGPT Work to automate everything
Claire Vo, joined by OpenAI's Nick Bowman, explores advanced use cases of Codex and ChatGPT Work, including voice-activated task delegation, multi-threaded AI…
Next 100x in AI: Inference, Networking, & Self-Optimizing Models — Philip Kiely & Ali Taha, Baseten
This episode of Latent Space features Philip Kiely and Ali Taha from Baseten, discussing advanced inference engineering for AI models. They delve into strategi…
OpenAI’s Vision for the AI Super App — Akshay Nathan, OpenAI
Akshay Nathan from OpenAI discusses the launch of ChatGPT Work, positioning it as an AI super app that merges ChatGPT and Codex capabilities to democratize the…
This CPO regrets that product management exists | Tom Verrilli (CPO of Whatnot)
In this episode, Tom Verrilli, CPO of Whatnot, shares his provocative stance that product management's widespread existence is regrettable, advocating for empo…
Building an Autonomous Enterprise for Real-World Services with Netic Founder Melisa Tokmak
Melisa Tokmak, founder and CEO of Netic, discusses how her company builds AI to autonomously run real-world service businesses like HVAC and pet care. She expl…
The AI Frontier: from open weights to open research — Eiso Kant, Poolside AI
Eiso Kant, CEO of Poolside AI, discusses his company's mission to foster an open and competitive AI landscape, moving away from an oligopoly of intelligence. H…
I hate Opus 5. It’s the best model, anyway.
Claire Vo opens up about her exhaustion with the rapid release of new AI models, proposing a future shift in focus from raw intelligence to factors like speed,…
Building an Autonomous Delivery Experience with DoorDash Co-Founders Andy Fang and Stanley Tang
DoorDash co-founders Andy Fang and Stanley Tang discuss the company's ambitious foray into Agentic Commerce and autonomous delivery with their robot, DOT. They…
🔬Causal Models Need Causal Data - Xaira’s X-Cell model (Bo Wang & Ci Chu)
This episode delves into Zera Therapeutics' AI drug discovery platform, focusing on their X-Cell model. Guests Bo Wang and Ci Chu explain how X-Cell leverages…
How Anthropic builds products like Claude Code before the AI models are ready | Dianne Penn
In this episode, Dianne Penn, head of product for Anthropic's AI research and labs teams, discusses Anthropic's journey from underdog to a leading AI company.…
The AI Memory Problem: Why Long Context Isn’t Enough — Dan Biderman, Engram Co-founder & CEO
During a cooking session, Engram co-founder and CEO Dan Biderman discusses his entrepreneurial journey from Israeli Naval Special Operations to leading an AI s…
🔬 RL with Verifiable Rewards, but the Verifier is a Lab — Lila Sciences
This episode explores Lila Sciences' ambitious thesis of creating AI Science Factories, transforming labs into data centers that generate internet-scale, exper…
Why Netflix is betting on systems thinkers—not specialists—in the AI era | Elizabeth Stone (CPTO)
Lenny Rachitsky and Elizabeth Stone, CPTO of Netflix, discuss the profound impact of AI on technology roles, organizational culture, and the future of entertai…
Local AI models explained: How to run a fleet of Mac Studios and GPUs at home
In this episode, Claire Vo and Alex Finn explore the practicalities of running local AI models at home, discussing the necessary hardware, setup processes, and…
How I run autonomous coding agents from my phone with OpenAI Symphony + Linear
Claire Vo and Alessio Finelli discuss how Alessio uses OpenAI's Symphony and Linear to manage autonomous coding agents, streamlining software development tasks…
The 100,000 Sandbox Problem — Akshat Bubna, Modal CTO
Akshat Bubna, CTO of Modal, discusses the company's evolution from a developer experience platform to one optimized for agent experience and specialized AI wor…
Podcast Crossover: AIE, AGI, frontier lab strategy with @matthew_berman and @swyxtv
In this crossover episode, Swyx, the founder of the AI Engineering Conference (AIE), discusses the origins and challenges of building the event. He delves into…
Why AI Agents Don't Actually Understand You — Danielle Perszyk, Amazon AGI Lab
Danielle Perszyk from Amazon AGI Lab discusses her vision for AI, emphasizing human collective intelligence and building agents that genuinely understand user…
Travel Through the Lens of AI with with Booking.com CEO Glenn Fogel
In this episode, Glenn Fogel, CEO of Booking Holdings, discusses the company's journey from Priceline to a global travel giant and its strategic approach to th…
Why the tech workforce is quietly splitting in two | Annual AI sentiment survey (Noam Segal)
This episode delves into the findings of the second annual tech worker sentiment survey conducted by Lenny Rachitsky and Noam Segal, revealing a deeply bifurca…
🔬 "The Most Innovative Diffusion Research Is Happening in Drug Discovery, Not Image Generation"
This episode explores how Genesis Molecular AI is leveraging advanced AI, particularly diffusion models, to revolutionize drug discovery by achieving unprecede…
How Nuclear Will Unlock Energy Abundance with Valar Atomics Founder Isaiah Taylor
This episode features Sarah Guo interviewing Isaiah Taylor, founder and CEO of Valor Atomics, about their work in developing scalable nuclear reactors. They di…
Cooking with OpenAI’s Research Chief: AGI, o1, Evals, and Scaling Laws — Mark Chen
OpenAI's Chief Research Officer, Mark Chen, joins Alessio Fanelli for a cooking session while discussing OpenAI's core research strategies. Topics include the…
Why Traditional Benchmarks Fail Modern AI Models with OpenAI Research Scientist Noam Brown
This episode features OpenAI research scientist Noam Brown discussing the shortcomings of current AI model evaluation benchmarks, particularly their failure to…
The Agent Cloud: Databricks’ Bet on the Future of AI — Matei Zaharia and Reynold Xin
This episode features Databricks co-founders Matei Zaharia and Reynold Xin discussing their latest innovations, including the Omnigents platform for agent deve…
AI Security After Codex and Claude Code — Zico Kolter & Matt Fredrikson, Gray Swan
This episode explores the evolving landscape of AI security with Gray Swan founders Zico Kolter and Matt Fredrikson. They discuss how AI systems introduce new…
OpenAI Codex lead on the new shape of product work | Andrew Ambrosino
This episode features Lenny Rachitsky and Andrew Ambrosino, product and engineering lead for the OpenAI Codex app. They discuss how AI, particularly Codex, is…
Loop engineering for beginners
This episode explores the concept of AI agent loops, contrasting them with traditional prompting and explaining how agents can be designed to prompt themselves…
🔬 The Limits of AI in Science - Why We Need Self-Driving Labs — Joseph Krause, Radical AI
Joseph Krause, CEO of Radical AI, discusses the inherent challenges of applying AI to material science compared to biology, emphasizing the necessity of experi…
⚡️Every product of the future will be a living system — Ronak Malde, Trajectory.ai
Ronak Malde, co-founder of Trajectory.ai, discusses his journey from Windsurf to DeepMind and ultimately to building Trajectory.ai. The conversation centers on…
How this startup uses AI agents to eliminate bugs and optimize infrastructure
Claire Vo and Anker Goyel discuss how AI agents are transforming software engineering, particularly for complex infrastructure and database optimization. Goyel…
Building the most AI-pilled engineering team in the world | Fiona Fung (Anthropic)
Fiona Fung, leader of Claude Code and Co-work teams at Anthropic, discusses the profound transformation of software engineering due to AI. She shares insights…
Re-engineering the Semiconductor Supply Chain with Intel CEO Lip Bu Tan
Intel CEO Lip Bu Tan discusses his ambitious plan to revitalize Intel, focusing on cultural shifts, balance sheet strengthening through strategic partnerships…
Why AI Labs With Unlimited GPUs Still Fail — Anjney Midha, AMP
In this episode, Anjney Midha, CEO of Amp, discusses why many AI labs struggle despite abundant resources, attributing failures to a lack of culture and organi…
Biohub: The Future of Biology is Open-Source with Mark Zuckerberg, Priscilla Chan, and Alex Rives
Mark Zuckerberg, Priscilla Chan, and Alex Rives discuss Biohub's mission to accelerate scientific progress through open-source tools and frontier AI combined w…
The hidden pattern behind successful products | Mark Pincus (FarmVille, Words with Friends, & more)
Mark Pincus, founder of Zynga, shares his 'Proven, Better, New' framework for product development, advocating for copying proven elements, making small improve…
She built a Claude shopping assistant to stop buying cheap junk
Nicole Ruiz shares how she leverages AI, specifically Claude, to create a personalized shopping assistant that curates high-quality, long-lasting products, avo…
Scaling Past Informal AI - Carina Hong, Axiom Math
This episode features Carina Hong, CEO of Axiom Math, discussing her company's vision for formal verification as the foundation for superintelligence and AGI,…
⚡️Making DeepSeek v4 outperform Opus 4.7 with Taste — @AhmadAwais , CommandCode.ai
Ahmad Awais discusses Command Code's "Taste" system for personalizing AI coding agents through automatically learned developer preferences. He reveals a novel…
Tony Fadell: How to build real taste (and why AI makes it matter more)
Tony Fadell, co-creator of the iPod, iPhone, and Nest, discusses the principles of building great products, from ideation using "pain and new technology" to th…
When AI Agents Run Businesses — Lukas Petersson and Axel Backlund of Andon Labs
Lukas Petersson and Axel Backlund of Andon Labs discuss their work evaluating AI agents, from simulated vending machine businesses to real-world robot deployme…
GitHub’s Agent Era: 14x Commits, 200M Developers, Copilot’s Next Act — Kyle Daigle
This episode features Kyle Daigle, CEO of GitHub and CMO of Developer for Microsoft, discussing the transformative impact of AI on software development and Git…
Satya Nadella on AI: @NoPriorsPodcast x Latent Space Crossover Special at Microsoft Build 2026
In this crossover episode, Satya Nadella, CEO of Microsoft, discusses the company's AI strategy, emphasizing an ecosystem approach for custom intelligence rath…
The Rise of the Full-Stack Builder and Hyper-Leveraged Generalist with Microsoft CEO Satya Nadella
Microsoft CEO Satya Nadella discusses the company's AI strategy, focusing on an ecosystem play where companies can build their own AI using specialized 'harnes…
🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
This episode features Alex Rives from Biohub discussing the application of the 'bitter lesson' (scaling laws and empirical evidence) to protein biology through…
Building an AI Guardian for Enterprise with Onyx Security CEO Maxim Bar Kogan
This episode features Sarah Guo interviewing Maxim Bar Kogan, CEO of Onyx Security, about the escalating security risks of autonomous AI agents in enterprise.…
Devin’s 80% Moment: Background Agents, 7x PRs, & End of Hand-Held Coding — Walden Yan & Cole Murray
This episode delves into the rapid evolution of AI coding agents, highlighted by Devin's increasing autonomy and efficiency. Guests Walden Yan and Cole Murray…
A rational conversation on where AI is actually going | Benedict Evans
Benedict Evans, a long-time tech analyst, shares his nuanced perspective on AI, comparing its impact to previous platform shifts like the internet and mobile.…
⚡️ Google's Open AI Strategy — Omar Sanseviero, Google DeepMind
Omar Sanseviero from Google DeepMind discusses the release and capabilities of Gemma 4, including its novel E2B architecture for on-device inference, its multi…
Amex Global Business Travel: The World’s First AI Take Private with Long Lake CEO Alexander Taubman
Long Lake CEO Alexander Taubman discusses his firm's unique AI-driven acquisition strategy, exemplified by the $6.3 billion take-private of American Express Gl…
Pax Silica: Inside the Trump Administration’s Tech Strategy with Jacob Helberg
Jacob Helberg, Under Secretary of State for Economic Affairs, discusses the Trump administration's "Pax Silica" initiative, a multi-nation coalition aimed at s…
Inside Abridge: The AI Listening to 100 Million Doctor Visits — Abridge's Janie Lee & Chai Asawa
This episode features a conversation with Janie Lee and Chai Asawa from Abridge, an AI company revolutionizing healthcare documentation and clinical intelligen…
Why we’re at the beginning of the AI hardware boom | Caitlin Kalinowski (ex–OpenAI, Meta, Apple)
This episode features a deep dive with Caitlin Kalinowski, an accomplished hardware leader, discussing the burgeoning AI hardware boom. The conversation explor…
Spec-driven development: the AI engineering workflow at Notion | Ryan Nystrom
Claire Vo and Ryan Nystrom, an engineering manager at Notion, discuss how AI has revolutionized their engineering workflows. They cover an AI agent that automa…
The internal AI tool that's transforming how Stripe designs products | Owen Williams
Claire Vo interviews Owen Williams, a design manager at Stripe, about "Protodash," an internal AI-powered prototyping tool he built. They discuss how Protodash…
🔬How GPT‑5 derived new results in theoretical physics and quantum gravity — Alex Lupsasca, OpenAI
Alex Lupsasca from OpenAI discusses how GPT models have achieved superhuman capabilities in theoretical physics, detailing two groundbreaking papers on gluon a…
How to build a company that withstands any era | Eric Ries, Lean Startup author
Lenny Rachitsky and Eric Ries discuss the ideas from Ries's new book, "Incorruptible," which addresses how successful companies often lose their mission and co…
How Sendbird became an AI-first company | John Kim (co-founder and CEO)
In this episode, Claire Vo interviews John Kim, co-founder and CEO of Sendbird, about their journey to becoming an AI-first company. They discuss Sendbird's in…
⚡️ Matt Pocock - Why Engineering Fundamentals matter MORE now
This episode features Matt Pocock discussing the enduring relevance of engineering fundamentals in the AI era, challenging the notion that AI negates the need…
Why cultivating agency matters more than cultivating skills in the AI era | Max Schoening (Notion)
In this episode, Lenny Rachitsky and Max Schoening discuss the profound impact of AI on product development, emphasizing that 'agency' is more crucial than tra…
Baseten CEO Tuhin Srivastava on Custom Models, and Building the Inference Cloud
Tuhin Srivastava, CEO of Baseten, discusses the explosive growth of the AI inference market, predicting over $1 billion in revenue for his company this year. H…
The $15B Physical AI Company: Simulation, Autonomy OS, Neural Sim, & 1K Engineers—Applied Intuition
This episode features Peter Ludwig and Qasar Younis, co-founders of Applied Intuition, a $15B company building "physical AI" for autonomous machines across var…
How a non-technical founder built a $100K ARR meme company | Jason Levin (Memelord CEO)
In this unhinged episode, Jason Levin, founder and CEO of Memelord, shares his journey as a non-technical founder building a meme company to $100K ARR using no…
⚡️ Competing with ChatGPT and Sierra, building a $10M ARR company — Yasser Elsaid, Founder, Chatbase
Yasser Elsaid, founder of Chatbase, discusses his journey from a bootstrapped side project to a $10M ARR AI customer service company. He shares insights into C…
How to build a defensible company in the AI era | Evan Spiegel (Snapchat CEO)
Lenny Rachitsky interviews Evan Spiegel, CEO and co-founder of Snap, exploring the challenges of building durable consumer social products in the current tech…
How Anthropic’s product team moves faster than anyone else | Cat Wu (Head of Product, Claude Code)
Cat Wu, Head of Product for Claude Code at Anthropic, discusses the incredibly fast pace of product development in AI, the evolving role of Product Managers, a…