Issue No. 44Week ending Sunday, November 1, 2026758 episodes · 3,331 write-ups
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Why 95% of AI Projects Fail, Anthropic still at $2T?, and Why AI Is Still in the First Inning

With David Weisburd, Joseph Coyne · Friday, November 6, 2026

Studio VC Co-Founder and Managing Partner Joseph Coyne sits down with host David Weisburd to explore why enterprise AI remains in its earliest innings. They examine why 95% of enterprise AI pilots fail, how proprietary data behind corporate firewalls creates enduring moats, and how physical AI applications in healthcare and motion capture are paving the way for next-generation robotics. Coyne and Weisburd also analyze venture valuations, business model transitions from SaaS to usage-based pricing, and how to underwrite foundation models like Anthropic and OpenAI.

Key takeaways

  • More than 80% of the world's data remains locked behind corporate firewalls, out of reach for public foundation models such as Anthropic and OpenAI. Read more →
  • Roughly 95% of enterprise AI pilots fail because corporate buyers deploy generic foundation models against standard workflows without proprietary data behind the firewall. Read more →
  • Late-stage foundation model rounds require massive market capture assumptions that clash with near-zero switching costs across major LLMs. Read more →
  • Ninety-five percent of enterprise AI pilots fail to reach production because pure technical tools fail to address legacy workflows and regulatory constraints. Read more →

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