Issue No. 37Week ending Sunday, September 13, 2026434 episodes · 1825 articles
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The Podcast Summary.

40 hours of podcasts, in 5 minutes.

Guest

Brian Armstrong

Brian Armstrong appears in 1 full episode we cover on No Priors. Below is what each conversation covered, with a key takeaway per article. Every quote in the articles is verbatim and timestamped to the source video.

1 episodecovered
6 articleswith timestamped quotes
AINo Priors

Coinbase’s Everything Exchange: Agentic Finance, Stablecoins & Tokenization with CEO Brian Armstrong

Coinbase co-founder and CEO Brian Armstrong joins Elad Gil to discuss the convergence of artificial intelligence and crypto infrastructure. They explore the creation of the 'Everything Exchange' through real-world asset tokenization, banking autonomous AI agents via crypto rails, and building recursive self-improvement engineering workflows inside Coinbase. Armstrong also outlines his biotech venture New Limit, detailing its epigenetic reprogramming roadmap and the macroeconomic potential of regulatory sandboxes like special economic zones.

  • Credit and debit card rails charge a fixed fee of roughly 30 cents plus a percentage per swipe, making any transaction under one dollar economically impossible. Read →
  • New Limit builds on Yamanaka factor research to restore aged cell function without erasing cellular identity or causing tumor formation. Read →
  • Coinbase launched an internal prediction market product that reached a $100 million revenue run rate within months of going live. Read →
  • Bitcoin trading generates only 12% of Coinbase revenue today, while 88% now comes from non-Bitcoin trading. Read →
  • Coinbase is overhauling its software development lifecycle by giving AI agents dedicated repository "brains" written in markdown. Read →
  • Software founders can iterate in hours, but hard tech founders in energy and biotech face regulatory barriers that delay physical experiments for years. Read →
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