BusinessTBPN
This episode covers a wide range of tech and business topics, including the controversy surrounding Anthropic's co-founder's wife and its implications for AI, South Korea's unique policy for retail investors, leaked details of Tesla's flying Roadster, and the surprising business model behind The Lion King musical's immense success. The hosts also discuss absurd real estate prices in Palo Alto, a heated VC debate over Corgi's ETF pivot, and amusing Gen Z trends.
- Anthropic, an AI company that explicitly frames its mission around moral alignment, is facing intense public scrutiny over the past of Cammy Clark, wife of CEO Dario Amade. Read →
- Corgi, an insurer by origin, rapidly expanded into the ETF business, launching a wide range of niche funds from a 'Coffee Energy Drinks ETF' to a 'US War Machine ETF.' Read →
- The Lion King musical has grossed over $11 billion, making it the highest-earning entertainment title ever, far surpassing movie blockbusters. Read →
- A seemingly ordinary 5,500 sq ft house in Palo Alto recently listed for a staggering $16.5 million, drawing sharp comparisons to luxury private islands globally. Read →
TechAll-In Podcast
This episode delves into the critical debate around AI regulation, discussing a proposal for industry self-regulation versus government control and the alleged regulatory capture by some AI companies. The hosts also analyze the significant M&A activity in the payments industry with Stripe, Block, and Advent's bid for PayPal, examining its implications for competition and the future of digital businesses. Additionally, they cover major concerns regarding AI data privacy and enterprise costs, Apple's lawsuit against OpenAI for alleged trade secret theft, and the controversial moratorium on hyperscale data centers in New York, connecting it to broader energy issues and potential foreign influence campaigns.
- Researchers at Calico and Revel Pharma used Google's AlphaFold AI to discover a novel enzyme capable of degrading CML, a major advanced glycation end product (AGE) that accumulates in the extracellular matrix and drives aging. Read →
- Apple sued OpenAI for IP theft, and Grok Build leaked code. Your AI data is vulnerable. Use Sachi's Enterprise Roadmap to control compute and prevent leaks. Read →
AINo Priors
Mark Zuckerberg, Priscilla Chan, and Alex Rives discuss Biohub's mission to accelerate scientific progress through open-source tools and frontier AI combined with frontier biology. They delve into breakthroughs like ESM fold for protein design, the advantages of their non-profit model for broad impact, and their vision for personalized medicine by understanding biological systems hierarchically.
- Biohub began with an audacious goal from Mark Zuckerberg: to "cure, prevent and manage all disease by the end of the century," a vision Priscilla Chan admits was met with laughter by Nobel-winning scientists. Read →
- For breakthroughs in complex fields like frontier biology, a non-profit structure can achieve "bigger impact" by getting tools into more scientists' hands faster than a for-profit model. Read →